董明杰

副研究员

学习&工作经历：

2022.08-至今 人工智能与数字经济广东省实验室（深圳）-副研究员(智慧医疗团队)

2020.07-2022.07 深圳大学-生物医学工程-博士后

2014.09-2020.06 浙江大学-化学-理学博士

2010.09-2014.06 浙江大学-化学-理学学士

邮箱：dongmingjie@gml.ac.cn

研究领域：

1.金属-有机框架材料（MOFs）、有机聚合物胶束等纳米递送载体的设计合成

2.肿瘤疫苗的设计合成

代表性成果：

1.M.-J. Dong, M. Zhao, S. Ou, C. Zou, C.-D. Wu, A Luminescent Dye@MOF Platform: Emission Fingerprint Relationships of Volatile Organic Molecules. Angew. Chem. Int. Ed. 2014, 53, 1575-1579.

2.M.-J. Dong, X. Wang, C.-D. Wu, Creation of Redox-Active PdSx Nanoparticles Inside the Defect Pores of MOF UiO-66 with Unique Semihydrogenation Catalytic Properties. Adv. Funct. Mater. 2019, 1908519.

3.M.-J. Dong, W. Li, Q. Xiang, Y. Tan, X. Xing, C. Wu, H. Dong, X. Zhang, Engineering Metal–Organic Framework Hybrid AIEgens with Tumor-Activated Accumulation and Emission for Image-Guided GSH Depletion ROS Therapy. ACS Appl. Mater. Interfaces 2022, 14, 29599-29612.

4.M.-J. Dong, X. Wang, H. Dong, X. Zhang, Applications of Metal-organic Frameworks in Cancer Theranostics. Chem. J. Chinese Universities, 2022, 43, 20220575.

发表论文论著：

1.M.-J. Dong, M. Zhao, S. Ou, C. Zou, C.-D. Wu, A Luminescent Dye@MOF Platform: Emission Fingerprint Relationships of Volatile Organic Molecules. Angew. Chem. Int. Ed. 2014, 53, 1575-1579.

2.M.-J. Dong, X. Wang, C.-D. Wu, Creation of Redox-Active PdSx Nanoparticles Inside the Defect Pores of MOF UiO-66 with Unique Semihydrogenation Catalytic Properties. Adv. Funct. Mater. 2019, 1908519.

3.M.-J. Dong, W. Li, Q. Xiang, Y. Tan, X. Xing, C. Wu, H. Dong, X. Zhang, Engineering Metal–Organic Framework Hybrid AIEgens with Tumor-Activated Accumulation and Emission for Image-Guided GSH Depletion ROS Therapy. ACS Appl. Mater. Interfaces 2022, 14, 29599-29612.

4.M.-J. Dong, X. Wang, H. Dong, X. Zhang, Applications of Metal-organic Frameworks in Cancer Theranostics. Chem. J. Chinese Universities, 2022, 43, 20220575.

5.X. Wang, M.-J. Dong, C.-D. Wu, Tuning the Pore Structures and Photocatalytic Properties of a 2D Covalent Organic Framework with Multi-Branched Photoactive Moieties. Nanoscale 2020, 12, 16136-16142.

6.X. Wang, M.-J. Dong, K. Chen, Z.-K. Liu, C.-D. Wu, Passing the Framework Skeleton and Properties of Coordination Materials onto Organic Framework Materials. Chem. Commun. 2021, 57, 1348-1351.

7.Q. Xiang, W. Li, Y. Tan, J. Shi, M.-J. Dong, J. Cheng, J, Huang, W. Zhang, Y. Gong, Q. Yang, L. Yang, H. Dong, X. Zhang, Engineering of Upconversion Carbon Dots/Metal-Organic Frameworks “Peeled Pitaya-Like” Heterostructure for Mitochondria-Targeted Photodynamic Therapy. Chem. Eng. J. 2022, 444, 136706.

8.W. Li, M.-J. Dong, Y. Li, H. Dong, Macrophages-Cancer Membrane-Encapsulated Metal−Organic Frameworks with Copper-Depleting Moiety for Mitochondria-Targeted Therapeutics. Adv. Healthcare Mater. 2023, 2202986.